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linearmodels

Kevin Sheppard · Econometrics & causal inference

Python package by Kevin Sheppard adding panel data, instrumental-variable, system (SUR/3SLS) and asset-pricing estimators missing from statsmodels

NCSAFreeOpen sourceLocalNov 2, 2026

LiteLLM

BerriAI · Prompting, evaluation & observability

In-depth entry

Open-source Python SDK and self-hosted AI gateway that calls 100+ LLM providers in the OpenAI format, with routing, fallbacks, virtual keys, budgets, spend tracking and logging callbacks

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

llama.cpp

ggml-org (Georgi Gerganov and contributors) · Local LLM inference & serving

In-depth entry

C/C++ inference engine for LLMs and vision-language models with GGUF quantized weights, Metal, CUDA, Vulkan and other backends, a CLI and an OpenAI-compatible server

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

LlamaIndex

LlamaIndex, Inc. · Agent frameworks & orchestration

Open-source Python framework for retrieval-augmented agents over your data, with connectors, indexes, query engines and event-driven workflows, alongside the commercial LlamaParse document platform

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

LM Studio

Element Labs, Inc. · Local LLM inference & serving

In-depth entry

Proprietary desktop app for discovering, downloading and running local LLMs with llama.cpp and MLX engines, a chat UI, an OpenAI-compatible server, CLI, SDKs and a headless daemon

ProprietaryFreemiumPaidLocalBroken

Logseq

Logseq · Personal knowledge management

Open-source, outliner-based knowledge base storing notes as local Markdown or Org-mode files with block references, queries and a graph view

AGPL-3.0-onlyOpen sourceFreeLocalNov 2, 2026

marimo

marimo (acquisition by CoreWeave announced October 2025) · Notebooks & interactive computing

Reactive Python notebook stored as a plain .py file that re-runs dependent cells automatically and doubles as a script or web app

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

MATLAB

MathWorks · Mathematical & statistical computing

MathWorks' commercial numeric computing environment and language for engineers and scientists, with toolboxes, Simulink integration, apps and MATLAB Online

ProprietaryPaidAcademicLocalNov 2, 2026

Matplotlib

Matplotlib Development Team (NumFOCUS) · Data visualization

The foundational Python plotting library for static, publication-quality figures with full control over every element, exported to PDF, SVG, PNG and PGF

Open sourceOpen sourceFreeLocalNov 2, 2026

Meilisearch

Meili SAS · Vector databases

Rust search engine for application search-as-you-type with typo tolerance, faceting and hybrid semantic search; MIT core plus BSL enterprise parts

MIT AND BUSL-1.1Open sourceFreeSelf-hostedNov 2, 2026

Mendeley

Elsevier · Citation management

Free reference manager from Elsevier with a desktop and web app, PDF annotation, a Web Importer, groups and bundled cloud storage

ProprietaryFreeLocalNov 2, 2026

Metabase

Metabase, Inc. · BI & dashboards

Self-hostable BI tool with a no-code question builder, SQL editor, dashboards and embedding; AGPL open-source edition plus commercial Pro and Enterprise

AGPL-3.0Open sourceFreeSelf-hostedNov 2, 2026

Microsoft 365

Microsoft · Productivity suites & task management

Microsoft's subscription suite of Office desktop and web apps, Exchange email, OneDrive, SharePoint and Teams with Copilot and Graph APIs

ProprietaryPaidEnterpriseLocalNov 2, 2026

Microsoft Power BI

Microsoft · BI & dashboards

Microsoft's business-intelligence suite: free Windows Power BI Desktop for modeling and reports, and the Power BI service in Microsoft Fabric for sharing

ProprietaryFreemiumPaidLocalBroken

Microsoft Teams

Microsoft · Collaboration & communication

Microsoft's chat, meetings and calling hub integrated with Microsoft 365, SharePoint and Entra ID, extensible through Microsoft Graph and Teams apps

ProprietaryFreemiumPaidBroken

Milvus

Zilliz / LF AI & Data Foundation · Vector databases

Open-source vector database from Zilliz with Lite, Standalone and Distributed deployments, many index types and GPU acceleration

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

MinIO (AIStor)

MinIO, Inc. · Backup & recovery

S3-compatible object storage server; the AGPL community edition was archived in April 2026 and succeeded by MinIO's AIStor Free and AIStor Enterprise editions

MixedFreeEnterpriseSelf-hostedRenamedBroken

MkDocs

MkDocs project (Tom Christie and contributors) · Documentation tooling

Python static site generator for project documentation that builds a navigable site from Markdown files and a single YAML configuration

BSD-2-ClauseOpen sourceFreeLocalNov 2, 2026

MongoDB

MongoDB, Inc. · NoSQL & key-value stores

Document database storing BSON documents with a rich aggregation pipeline, available as a source-available Community Server or the managed Atlas service

SSPL-1.0FreeFreemiumSelf-hostedBroken

MySQL

Oracle · Relational databases

Oracle's widely deployed open-source relational database server, offered as a GPL community edition and commercial enterprise and cloud editions

GPL-2.0-only WITH Universal-FOSS-exception-1.0Open sourceFreeSelf-hostedBroken

NATS

NATS project (CNCF; maintained principally by Synadia) · Messaging & queues

Lightweight Go messaging system with core pub/sub and request-reply plus JetStream persistence, key-value and object stores; a CNCF project

Apache-2.0Open sourceFreeSelf-hostedNov 2, 2026

Neo4j

Neo4j, Inc. · NoSQL & key-value stores

Native property-graph database queried with Cypher, offered as a GPL community edition, a commercial enterprise edition and the AuraDB cloud service

GPL-3.0Open sourceFreemiumSelf-hostedBroken

Neovim

Neovim project · IDEs & editors

Modal, terminal-based text editor forked from Vim with Lua configuration, a built-in LSP client and Tree-sitter parsing

Apache-2.0Open sourceFreeLocalNov 2, 2026

Next.js

Vercel · Web frameworks & UI

In-depth entry

React framework from Vercel for full-stack web applications with file-based routing, server components, server-side rendering, static generation and API route handlers

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

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