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Docker

Docker, Inc. · Containers & virtualization

In-depth entry

Container platform combining the Docker Engine runtime, the Compose and Build tooling, Docker Desktop for macOS and Windows, and the Docker Hub registry

Apache-2.0Open sourceFreemiumLocalSelf-hostedNov 2, 2026

exo

Exo Labs · Distributed & parallel computing

Open-source software that pools several Apple Silicon Macs (and Linux hosts) into one local inference cluster, sharding large models across devices with MLX

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

gretl

gretl developers (Allin Cottrell, Riccardo Lucchetti) · Econometrics & causal inference

Free, GPL-licensed cross-platform econometrics program with a GUI, the hansl scripting language and estimators for time series, panels and limited dependent variables

GPL-3.0-onlyFreeOpen sourceLocalNov 2, 2026

Hammerspoon

Hammerspoon contributors · macOS automation

Open-source macOS automation app that exposes system APIs to a Lua configuration file for hotkeys, window management and event-driven scripts

MITOpen sourceFreeLocalNov 2, 2026

JabRef

JabRef e.V. and contributors · Citation management

Open-source, BibTeX/biblatex-native reference manager for LaTeX users with online fetchers, groups, file linking and editor integration

MITFreeOpen sourceLocalNov 2, 2026

Karabiner-Elements

pqrs.org (Takayama Fumihiko) · macOS system utilities

Free, public-domain keyboard customizer for macOS that remaps keys and defines complex modifications through JSON rules at the driver level

UnlicenseOpen sourceFreeLocalNov 2, 2026

LM Studio

Element Labs, Inc. · Local LLM inference & serving

In-depth entry

Proprietary desktop app for discovering, downloading and running local LLMs with llama.cpp and MLX engines, a chat UI, an OpenAI-compatible server, CLI, SDKs and a headless daemon

ProprietaryFreemiumPaidLocalBroken

MATLAB

MathWorks · Mathematical & statistical computing

MathWorks' commercial numeric computing environment and language for engineers and scientists, with toolboxes, Simulink integration, apps and MATLAB Online

ProprietaryPaidAcademicLocalNov 2, 2026

Ollama

Ollama · Local LLM inference & serving

In-depth entry

Open-source runtime and model manager for running open-weight LLMs locally on macOS, Windows and Linux, with a REST API, OpenAI- and Anthropic-compatible endpoints and optional cloud models

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

Positron

Posit Software, PBC · Mathematical & statistical computing

Posit's multi-language data-science IDE built on Code OSS, with first-class R and Python consoles, variables and plots panes, under the Elastic License 2.0

Elastic-2.0FreeLocalNov 2, 2026

RStudio IDE

Posit Software, PBC · Mathematical & statistical computing

Posit's open-source integrated development environment for R, with console, editor, plots, environment panes, Quarto/R Markdown authoring and Python via reticulate

AGPL-3.0-onlyFreeOpen sourceLocalSelf-hostedNov 2, 2026

Stata

StataCorp LLC · Mathematical & statistical computing

Commercial statistical software from StataCorp widely used in economics and social science, with editions BE/SE/MP, a command language, Mata and comprehensive PDF manuals

ProprietaryPaidAcademicLocalNov 2, 2026

Tableau

Salesforce · BI & dashboards

Salesforce's visual analytics platform: Tableau Desktop authoring (now with a free edition), Tableau Cloud and Server for sharing, and Tableau Next for CRM analytics

ProprietaryFreemiumPaidLocalSelf-hostedNov 2, 2026

TeXstudio

TeXstudio contributors · LaTeX & typesetting

Open-source desktop LaTeX editor with integrated PDF viewer, autocompletion, wizards, spell checking and a structure view for Windows, macOS and Linux

GPL-3.0-onlyFreeOpen sourceLocalNov 2, 2026

WireGuard

WireGuard project (Jason A. Donenfeld) · Tunneling & remote access

In-depth entry

Minimal, high-speed VPN protocol and implementation built on modern cryptography, included in the Linux kernel and available on macOS, iOS, Windows, Android and BSD

GPL-2.0-onlyOpen sourceFreeLocalSelf-hostedNov 2, 2026

Wolfram Mathematica

Wolfram Research · Mathematical & statistical computing

Wolfram Research's proprietary technical computing system built on the Wolfram Language, with notebooks, symbolic and numeric computation, visualization, machine learning and curated data

ProprietaryPaidAcademicLocalNov 2, 2026

Zotero

Corporation for Digital Scholarship · Citation management

In-depth entry

Free, open-source reference manager with browser connectors, word-processor plugins, a PDF reader, group libraries and optional paid file storage

AGPL-3.0-onlyFreeOpen sourceLocalNov 2, 2026

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