Directory

Microsoft's multi-agent framework (Core, AgentChat, Extensions, Studio) for Python and .NET, now archived with users directed to Microsoft Agent Framework

YAML-configured open-source framework for fine-tuning and post-training LLMs: full, LoRA and QLoRA training, preference and RL methods, multimodal models and multi-GPU or multi-node runs

OpenAI's consumer and workplace assistant, available on the web, desktop and mobile, with projects, plugins, browsing, voice and the Codex coding agent

Open-source embedding database with a minimal Python and JavaScript API, usable in-process, as a server or through Chroma Cloud

Anthropic's consumer and team assistant on web, desktop and mobile, with projects, artifacts, memory, connectors and web search, sold on Pro, Max, Team and Enterprise plans

Open-source node-based interface and inference engine for diffusion and other generative models (image, video, audio, 3D), runnable locally with desktop apps or as a hosted cloud

Apple's on-device machine-learning runtime for iOS and macOS apps, with the open-source coremltools package for converting PyTorch and other models to its format

Apple's app and Swift framework for training image, text, sound, tabular and activity models on a Mac without writing training code, exporting directly to Core ML

Open-source Python framework for role-based multi-agent crews and event-driven flows, with a commercial enterprise console for deploying, monitoring and triggering automations

AI-native code editor from Anysphere, forked from VS Code, with inline edits, codebase-aware chat and agent mode that can run multi-step changes

Python framework for programming language-model pipelines with typed signatures and modules, then optimizing prompts and weights automatically against a metric

Open-source software that pools several Apple Silicon Macs (and Linux hosts) into one local inference cluster, sharding large models across devices with MLX

Apple's Swift framework giving apps access to the on-device Apple Intelligence language model with guided generation, tool calling and sessions, on OS 26 and later

Python library for extracting validated structured data from LLM responses using Pydantic models, with automatic retries, streaming partials and support for many providers

Python library for NumPy-style array computing with composable transformations (jit, grad, vmap, shard_map) compiled through XLA to CPU, GPU and TPU

Open-source Python and JavaScript framework whose create_agent harness builds tool-using agents on the LangGraph runtime with swappable model providers and middleware

Open-source Python framework for retrieval-augmented agents over your data, with connectors, indexes, query engines and event-driven workflows, alongside the commercial LlamaParse document platform

Open-source vector database from Zilliz with Lite, Standalone and Distributed deployments, many index types and GPU acceleration

Port of OpenAI's Whisper speech-recognition models to MLX, offering a CLI and Python API for local transcription on Apple Silicon

Lightweight open-source Python and TypeScript framework for agents, handoffs, guardrails, sessions and tracing, defaulting to OpenAI's Responses API with adapters for other providers

OpenAI's coding agent: an open-source Rust terminal CLI plus IDE extension, desktop app and cloud agent, signed in with a ChatGPT plan or an API key

Open-source, local-first CLI and library for evaluating prompts, models, RAG pipelines and agents, with automated red teaming and CI integration

Type-safe Python agent framework from the Pydantic team with validated structured outputs, dependency injection, swappable model providers, MCP, durable execution and evals

Open-source deep-learning framework with eager tensors, autograd, torch.compile and distributed training, governed by the PyTorch Foundation and the base of most LLM tooling