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Express

OpenJS Foundation · Web frameworks & UI

Minimal, unopinionated web framework for Node.js with routing and middleware, the long-standing default for HTTP servers in the Node ecosystem

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

FastAPI

Sebastián Ramírez (tiangolo) and FastAPI contributors · API development & tooling

In-depth entry

Python web framework for building HTTP APIs from type-annotated functions, with automatic validation through Pydantic and generated OpenAPI documentation

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

HashiCorp Vault

HashiCorp (an IBM company) · Secrets management

Identity-based secrets manager providing encrypted key-value storage, dynamic database and cloud credentials, PKI and encryption-as-a-service, under the Business Source License

BUSL-1.1FreePaidSelf-hostedNov 2, 2026

Hono

Hono project (Yusuke Wada and contributors) · Web frameworks & UI

Small TypeScript web framework built on Web Standard APIs that runs unchanged on Cloudflare Workers, Deno, Bun, Node.js and other JavaScript runtimes

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

Hoppscotch

Hoppscotch · API development & tooling

Open-source API client that runs in the browser or as a desktop app, supports REST, GraphQL and realtime protocols, and can be self-hosted for teams

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

LiteLLM

BerriAI · Prompting, evaluation & observability

In-depth entry

Open-source Python SDK and self-hosted AI gateway that calls 100+ LLM providers in the OpenAI format, with routing, fallbacks, virtual keys, budgets, spend tracking and logging callbacks

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

llama.cpp

ggml-org (Georgi Gerganov and contributors) · Local LLM inference & serving

In-depth entry

C/C++ inference engine for LLMs and vision-language models with GGUF quantized weights, Metal, CUDA, Vulkan and other backends, a CLI and an OpenAI-compatible server

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

Meilisearch

Meili SAS · Vector databases

Rust search engine for application search-as-you-type with typo tolerance, faceting and hybrid semantic search; MIT core plus BSL enterprise parts

MIT AND BUSL-1.1Open sourceFreeSelf-hostedNov 2, 2026

Model Context Protocol

Model Context Protocol, a Series of LF Projects, LLC (originated by Anthropic) · Agent frameworks & orchestration

In-depth entry

Open JSON-RPC standard for connecting AI applications to tools, data and prompts through servers, now stewarded under the Linux Foundation with SDKs in many languages

Open sourceOpen sourceFreeLocalSelf-hostedNov 2, 2026

Ollama

Ollama · Local LLM inference & serving

In-depth entry

Open-source runtime and model manager for running open-weight LLMs locally on macOS, Windows and Linux, with a REST API, OpenAI- and Anthropic-compatible endpoints and optional cloud models

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

OSF (Open Science Framework)

Center for Open Science · Reproducibility & research software

Free, open-source research management platform from the Center for Open Science for projects, preregistrations, registries, preprint services and linking outputs across storage providers

Apache-2.0FreeSelf-hostedNov 2, 2026

Overpass API

Roland Olbricht and the OpenStreetMap community · GIS & mapping

Read-only query service for OpenStreetMap data using the Overpass QL language, available on public instances or self-hosted

AGPL-3.0-onlyFreeOpen sourceSelf-hostedNov 2, 2026

Typesense

Typesense, Inc. · Vector databases

GPL-licensed in-memory search engine in C++ offering typo-tolerant instant search, faceting, vector and hybrid search, with Typesense Cloud hosting

GPL-3.0Open sourceFreeSelf-hostedNov 2, 2026

vLLM

vLLM project (originated at UC Berkeley Sky Computing Lab) · Local LLM inference & serving

In-depth entry

High-throughput LLM inference and serving engine with PagedAttention, continuous batching, quantization and an OpenAI-compatible server for GPU and accelerator clusters

Apache-2.0Open sourceFreeSelf-hostedNov 2, 2026

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