LangChain, Inc. · Agent frameworks & orchestration
Open-source Python and JavaScript framework whose create_agent harness builds tool-using agents on the LangGraph runtime with swappable model providers and middleware
LangChain, Inc. · Agent frameworks & orchestration
In-depth entry
Low-level orchestration framework and runtime for stateful, long-running agents expressed as graphs, with durable execution, checkpointing, human-in-the-loop and streaming
Open-source Python SDK and self-hosted AI gateway that calls 100+ LLM providers in the OpenAI format, with routing, fallbacks, virtual keys, budgets, spend tracking and logging callbacks
ggml-org (Georgi Gerganov and contributors) · Local LLM inference & serving
In-depth entry
C/C++ inference engine for LLMs and vision-language models with GGUF quantized weights, Metal, CUDA, Vulkan and other backends, a CLI and an OpenAI-compatible server
LlamaIndex, Inc. · Agent frameworks & orchestration
Open-source Python framework for retrieval-augmented agents over your data, with connectors, indexes, query engines and event-driven workflows, alongside the commercial LlamaParse document platform
Document database storing BSON documents with a rich aggregation pipeline, available as a source-available Community Server or the managed Atlas service
React framework from Vercel for full-stack web applications with file-based routing, server components, server-side rendering, static generation and API route handlers
Lightweight open-source Python and TypeScript framework for agents, handoffs, guardrails, sessions and tracing, defaulting to OpenAI's Responses API with adapters for other providers