Directory

Microsoft's multi-agent framework (Core, AgentChat, Extensions, Studio) for Python and .NET, now archived with users directed to Microsoft Agent Framework

YAML-configured open-source framework for fine-tuning and post-training LLMs: full, LoRA and QLoRA training, preference and RL methods, multimodal models and multi-GPU or multi-node runs

Open-source embedding database with a minimal Python and JavaScript API, usable in-process, as a server or through Chroma Cloud

Open-source node-based interface and inference engine for diffusion and other generative models (image, video, audio, 3D), runnable locally with desktop apps or as a hosted cloud

Open-source Python framework for role-based multi-agent crews and event-driven flows, with a commercial enterprise console for deploying, monitoring and triggering automations

Python framework for programming language-model pipelines with typed signatures and modules, then optimizing prompts and weights automatically against a metric

Open-source software that pools several Apple Silicon Macs (and Linux hosts) into one local inference cluster, sharding large models across devices with MLX

Python library for extracting validated structured data from LLM responses using Pydantic models, with automatic retries, streaming partials and support for many providers

Python library for NumPy-style array computing with composable transformations (jit, grad, vmap, shard_map) compiled through XLA to CPU, GPU and TPU

Open-source Python and JavaScript framework whose create_agent harness builds tool-using agents on the LangGraph runtime with swappable model providers and middleware

Open-source Python framework for retrieval-augmented agents over your data, with connectors, indexes, query engines and event-driven workflows, alongside the commercial LlamaParse document platform

Open-source vector database from Zilliz with Lite, Standalone and Distributed deployments, many index types and GPU acceleration

Port of OpenAI's Whisper speech-recognition models to MLX, offering a CLI and Python API for local transcription on Apple Silicon

Lightweight open-source Python and TypeScript framework for agents, handoffs, guardrails, sessions and tracing, defaulting to OpenAI's Responses API with adapters for other providers

Open-source, local-first CLI and library for evaluating prompts, models, RAG pipelines and agents, with automated red teaming and CI integration

Type-safe Python agent framework from the Pydantic team with validated structured outputs, dependency injection, swappable model providers, MCP, durable execution and evals

Open-source deep-learning framework with eager tensors, autograd, torch.compile and distributed training, governed by the PyTorch Foundation and the base of most LLM tooling

Open-source Python library for evaluating LLM and RAG applications with LLM-driven and custom metrics, experiments, dataset management and result tracking

BSD-licensed Python machine-learning library for classification, regression, clustering, dimensionality reduction, preprocessing and model selection on NumPy and SciPy

Python library for computing and training embedding, cross-encoder reranker, sparse and multi-vector retrieval models, maintained by Hugging Face with thousands of pretrained models on the Hub

Hugging Face's model-definition library for text, vision, audio, video and multimodal models, with Pipeline, Trainer and generate APIs used as the reference by training and inference engines

Open-source framework for fine-tuning and running LLMs with reduced memory, covering LoRA, QLoRA, full fine-tuning and RL, GGUF export, Dynamic quantizations and a local Studio/Desktop UI

Open-source vector database in Go with pluggable vectorizer modules, hybrid BM25 and vector search, multi-tenancy and a managed cloud

OpenAI's open-source multilingual speech recognition model family with MIT-licensed code and weights, a Python package and CLI for transcription, translation and language identification