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AutoGen

Microsoft · Agent frameworks & orchestration

Microsoft's multi-agent framework (Core, AgentChat, Extensions, Studio) for Python and .NET, now archived with users directed to Microsoft Agent Framework

MITOpen sourceFreeLocalSelf-hostedDeprecatedNov 2, 2026

CrewAI

CrewAI, Inc. · Agent frameworks & orchestration

Open-source Python framework for role-based multi-agent crews and event-driven flows, with a commercial enterprise console for deploying, monitoring and triggering automations

MITOpen sourceFreemiumLocalSelf-hostedNov 2, 2026

LiteLLM

BerriAI · Prompting, evaluation & observability

In-depth entry

Open-source Python SDK and self-hosted AI gateway that calls 100+ LLM providers in the OpenAI format, with routing, fallbacks, virtual keys, budgets, spend tracking and logging callbacks

MITOpen sourceFreeLocalSelf-hostedNov 2, 2026

Neo4j

Neo4j, Inc. · NoSQL & key-value stores

Native property-graph database queried with Cypher, offered as a GPL community edition, a commercial enterprise edition and the AuraDB cloud service

GPL-3.0Open sourceFreemiumSelf-hostedBroken

Qdrant

Qdrant Solutions GmbH · Vector databases

In-depth entry

Open-source vector search engine written in Rust with filterable HNSW indexes, sparse and multi-vector support, REST/gRPC APIs and a managed cloud

Apache-2.0Open sourceFreemiumLocalSelf-hostedNov 2, 2026

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