Directory

Microsoft's multi-agent framework (Core, AgentChat, Extensions, Studio) for Python and .NET, now archived with users directed to Microsoft Agent Framework

Open-source node-based interface and inference engine for diffusion and other generative models (image, video, audio, 3D), runnable locally with desktop apps or as a hosted cloud

Apple's on-device machine-learning runtime for iOS and macOS apps, with the open-source coremltools package for converting PyTorch and other models to its format

Apple's app and Swift framework for training image, text, sound, tabular and activity models on a Mac without writing training code, exporting directly to Core ML

Python framework for programming language-model pipelines with typed signatures and modules, then optimizing prompts and weights automatically against a metric

Open-source software that pools several Apple Silicon Macs (and Linux hosts) into one local inference cluster, sharding large models across devices with MLX

Apple's Swift framework giving apps access to the on-device Apple Intelligence language model with guided generation, tool calling and sessions, on OS 26 and later

Python library for extracting validated structured data from LLM responses using Pydantic models, with automatic retries, streaming partials and support for many providers

Python library for NumPy-style array computing with composable transformations (jit, grad, vmap, shard_map) compiled through XLA to CPU, GPU and TPU

Open-source Python and JavaScript framework whose create_agent harness builds tool-using agents on the LangGraph runtime with swappable model providers and middleware

Low-level orchestration framework and runtime for stateful, long-running agents expressed as graphs, with durable execution, checkpointing, human-in-the-loop and streaming

Open-source Python SDK and self-hosted AI gateway that calls 100+ LLM providers in the OpenAI format, with routing, fallbacks, virtual keys, budgets, spend tracking and logging callbacks

C/C++ inference engine for LLMs and vision-language models with GGUF quantized weights, Metal, CUDA, Vulkan and other backends, a CLI and an OpenAI-compatible server

Open-source Python framework for retrieval-augmented agents over your data, with connectors, indexes, query engines and event-driven workflows, alongside the commercial LlamaParse document platform

Open-source vector database from Zilliz with Lite, Standalone and Distributed deployments, many index types and GPU acceleration

Apple's open-source array framework for machine learning on Apple Silicon, with NumPy-like Python, C++ and Swift APIs and unified CPU/GPU memory

Python package and CLI for running, serving, quantizing and fine-tuning large language models on Apple Silicon with MLX

Port of OpenAI's Whisper speech-recognition models to MLX, offering a CLI and Python API for local transcription on Apple Silicon

Open JSON-RPC standard for connecting AI applications to tools, data and prompts through servers, now stewarded under the Linux Foundation with SDKs in many languages

Open-source runtime and model manager for running open-weight LLMs locally on macOS, Windows and Linux, with a REST API, OpenAI- and Anthropic-compatible endpoints and optional cloud models

Lightweight open-source Python and TypeScript framework for agents, handoffs, guardrails, sessions and tracing, defaulting to OpenAI's Responses API with adapters for other providers

Open-source, local-first CLI and library for evaluating prompts, models, RAG pipelines and agents, with automated red teaming and CI integration

Type-safe Python agent framework from the Pydantic team with validated structured outputs, dependency injection, swappable model providers, MCP, durable execution and evals

Open-source deep-learning framework with eager tensors, autograd, torch.compile and distributed training, governed by the PyTorch Foundation and the base of most LLM tooling