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PyTorch

PyTorch Foundation (Linux Foundation) · Training & fine-tuning

Open-source deep-learning framework with eager tensors, autograd, torch.compile and distributed training, governed by the PyTorch Foundation and the base of most LLM tooling

BSD-3-ClauseOpen sourceFreeLocalSelf-hostedBroken

QGIS

QGIS.org association · GIS & mapping

In-depth entry

Open-source desktop GIS for viewing, editing, analysing and publishing vector and raster geodata, extensible with Python plugins

GPL-2.0-or-laterOpen sourceFreeLocalBroken

QuantConnect

QuantConnect Corporation · Financial analysis & investing

In-depth entry

Algorithmic trading platform built on the open-source LEAN engine, with cloud backtesting, research notebooks and brokerage-connected live trading

Apache-2.0FreemiumPaidLocalNov 2, 2026

QuantLib

QuantLib project (Luigi Ballabio and contributors) · Financial analysis & investing

In-depth entry

Open-source C++ library for quantitative finance covering instruments, term structures, pricing engines and calendars, with Python and other bindings

BSD-3-ClauseOpen sourceFreeLocalNov 2, 2026

Quarto

Posit Software, PBC · Academic writing & publishing

In-depth entry

Open-source scientific publishing system from Posit that renders Markdown with executable Python, R, Julia or Observable code to HTML, PDF, Word, slides, websites and books via Pandoc

MITFreeOpen sourceLocalNov 2, 2026

Ragas

Vibrant Labs (formerly Exploding Gradients) · Prompting, evaluation & observability

Open-source Python library for evaluating LLM and RAG applications with LLM-driven and custom metrics, experiments, dataset management and result tracking

Apache-2.0Open sourceFreeLocalBroken

Ray

Ray project (Anyscale and contributors) · Distributed & parallel computing

In-depth entry

Open-source Python framework for distributing tasks, actors and ML workloads across a cluster, with libraries for data processing, training, tuning, serving and reinforcement learning

Apache-2.0Open sourceFreeLocalSelf-hostedBroken

Riskfolio-Lib

Dany Cajas · Portfolio & wealth management

Python library for quantitative portfolio optimization with many risk measures, robust estimators and hierarchical clustering models

BSD-3-ClauseOpen sourceFreeLocalNov 2, 2026

scikit-learn

scikit-learn developers · Mathematical & statistical computing

BSD-licensed Python machine-learning library for classification, regression, clustering, dimensionality reduction, preprocessing and model selection on NumPy and SciPy

BSD-3-ClauseFreeOpen sourceLocalNov 2, 2026

SciPy

SciPy developers (NumFOCUS) · Mathematical & statistical computing

Core open-source Python library for scientific computing on NumPy arrays: optimization, integration, interpolation, linear algebra, sparse matrices, statistics, signal processing

BSD-3-ClauseFreeOpen sourceLocalNov 2, 2026

Scrapy

Scrapy developers (maintained with Zyte) · Data collection & crawling

In-depth entry

Mature open-source Python framework for writing crawlers (spiders) that fetch pages asynchronously, extract structured items and export them through pipelines

BSD-3-ClauseOpen sourceFreeLocalSelf-hostedNov 2, 2026

Sentence Transformers

Hugging Face · Embeddings, reranking & retrieval

Python library for computing and training embedding, cross-encoder reranker, sparse and multi-vector retrieval models, maintained by Hugging Face with thousands of pretrained models on the Hub

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

Sphinx

Sphinx team · Documentation tooling

Python documentation generator using reStructuredText or MyST Markdown with cross-referencing, API autodoc and output to HTML, PDF via LaTeX, ePub and man pages

BSD-2-ClauseOpen sourceFreeLocalNov 2, 2026

statsmodels

statsmodels developers (NumFOCUS) · Econometrics & causal inference

In-depth entry

Python library for estimating statistical and econometric models with R-style formulas, rich result summaries and tests: OLS, GLM, discrete choice, ARIMA, state space, VAR and more

BSD-3-ClauseFreeOpen sourceLocalNov 2, 2026

SymPy

SymPy Development Team · Mathematical & statistical computing

Pure-Python computer algebra system for symbolic algebra, calculus, equation solving, matrices, physics modules, code generation and LaTeX output

BSD-3-ClauseFreeOpen sourceLocalNov 2, 2026

Transformers

Hugging Face · Training & fine-tuning

Hugging Face's model-definition library for text, vision, audio, video and multimodal models, with Pipeline, Trainer and generate APIs used as the reference by training and inference engines

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

Unsloth

Unsloth AI · Training & fine-tuning

Open-source framework for fine-tuning and running LLMs with reduced memory, covering LoRA, QLoRA, full fine-tuning and RL, GGUF export, Dynamic quantizations and a local Studio/Desktop UI

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

uv

Astral · Programming languages & runtimes

In-depth entry

Rust-based Python package and project manager from Astral that replaces pip, venv, pip-tools and pyenv with one command-line tool

MIT OR Apache-2.0Open sourceFreeLocalNov 2, 2026

vectorbt

Oleg Polakow · Financial analysis & investing

Python library for vectorized backtesting and portfolio analysis built on pandas, NumPy and Numba, with a commercial PRO edition

Apache-2.0 WITH Commons-ClauseFreePaidLocalNov 2, 2026

Vega-Altair

Vega-Altair developers (Vega project) · Data visualization

Declarative Python visualization library that compiles concise chart specifications to Vega-Lite JSON for interactive, grammar-of-graphics plots

BSD-3-ClauseOpen sourceFreeLocalNov 2, 2026

Whisper

OpenAI · Voice, vision & multimodal AI

OpenAI's open-source multilingual speech recognition model family with MIT-licensed code and weights, a Python package and CLI for transcription, translation and language identification

MITOpen sourceFreeLocalMaintenanceNov 2, 2026

yfinance

Ran Aroussi and contributors · Market & fundamentals data

Open-source Python library that downloads price history, fundamentals, options chains and fund data from Yahoo Finance's unofficial endpoints for research and education

Apache-2.0FreeOpen sourceLocalNov 2, 2026

Zipline Reloaded

Stefan Jansen (ML4Trading) · Financial analysis & investing

Community-maintained fork of Quantopian's Zipline, an event-driven Python backtester with data bundles and the Pipeline API

Apache-2.0Open sourceFreeLocalBroken

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