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Python

Python Software Foundation · Programming languages & runtimes

In-depth entry

General-purpose, dynamically typed programming language with a large standard library and the dominant ecosystem for data science and machine learning

PSF-2.0Open sourceFreeLocalSelf-hostedBroken

PyTorch

PyTorch Foundation (Linux Foundation) · Training & fine-tuning

Open-source deep-learning framework with eager tensors, autograd, torch.compile and distributed training, governed by the PyTorch Foundation and the base of most LLM tooling

BSD-3-ClauseOpen sourceFreeLocalSelf-hostedBroken

QGIS

QGIS.org association · GIS & mapping

In-depth entry

Open-source desktop GIS for viewing, editing, analysing and publishing vector and raster geodata, extensible with Python plugins

GPL-2.0-or-laterOpen sourceFreeLocalBroken

QuantConnect

QuantConnect Corporation · Financial analysis & investing

In-depth entry

Algorithmic trading platform built on the open-source LEAN engine, with cloud backtesting, research notebooks and brokerage-connected live trading

Apache-2.0FreemiumPaidLocalNov 2, 2026

QuantLib

QuantLib project (Luigi Ballabio and contributors) · Financial analysis & investing

In-depth entry

Open-source C++ library for quantitative finance covering instruments, term structures, pricing engines and calendars, with Python and other bindings

BSD-3-ClauseOpen sourceFreeLocalNov 2, 2026

Ragas

Vibrant Labs (formerly Exploding Gradients) · Prompting, evaluation & observability

Open-source Python library for evaluating LLM and RAG applications with LLM-driven and custom metrics, experiments, dataset management and result tracking

Apache-2.0Open sourceFreeLocalBroken

Ray

Ray project (Anyscale and contributors) · Distributed & parallel computing

In-depth entry

Open-source Python framework for distributing tasks, actors and ML workloads across a cluster, with libraries for data processing, training, tuning, serving and reinforcement learning

Apache-2.0Open sourceFreeLocalSelf-hostedBroken

Riskfolio-Lib

Dany Cajas · Portfolio & wealth management

Python library for quantitative portfolio optimization with many risk measures, robust estimators and hierarchical clustering models

BSD-3-ClauseOpen sourceFreeLocalNov 2, 2026

scikit-learn

scikit-learn developers · Mathematical & statistical computing

BSD-licensed Python machine-learning library for classification, regression, clustering, dimensionality reduction, preprocessing and model selection on NumPy and SciPy

BSD-3-ClauseFreeOpen sourceLocalNov 2, 2026

SciPy

SciPy developers (NumFOCUS) · Mathematical & statistical computing

Core open-source Python library for scientific computing on NumPy arrays: optimization, integration, interpolation, linear algebra, sparse matrices, statistics, signal processing

BSD-3-ClauseFreeOpen sourceLocalNov 2, 2026

Scrapy

Scrapy developers (maintained with Zyte) · Data collection & crawling

In-depth entry

Mature open-source Python framework for writing crawlers (spiders) that fetch pages asynchronously, extract structured items and export them through pipelines

BSD-3-ClauseOpen sourceFreeLocalSelf-hostedNov 2, 2026

Sentence Transformers

Hugging Face · Embeddings, reranking & retrieval

Python library for computing and training embedding, cross-encoder reranker, sparse and multi-vector retrieval models, maintained by Hugging Face with thousands of pretrained models on the Hub

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

Sphinx

Sphinx team · Documentation tooling

Python documentation generator using reStructuredText or MyST Markdown with cross-referencing, API autodoc and output to HTML, PDF via LaTeX, ePub and man pages

BSD-2-ClauseOpen sourceFreeLocalNov 2, 2026

statsmodels

statsmodels developers (NumFOCUS) · Econometrics & causal inference

In-depth entry

Python library for estimating statistical and econometric models with R-style formulas, rich result summaries and tests: OLS, GLM, discrete choice, ARIMA, state space, VAR and more

BSD-3-ClauseFreeOpen sourceLocalNov 2, 2026

SymPy

SymPy Development Team · Mathematical & statistical computing

Pure-Python computer algebra system for symbolic algebra, calculus, equation solving, matrices, physics modules, code generation and LaTeX output

BSD-3-ClauseFreeOpen sourceLocalNov 2, 2026

Transformers

Hugging Face · Training & fine-tuning

Hugging Face's model-definition library for text, vision, audio, video and multimodal models, with Pipeline, Trainer and generate APIs used as the reference by training and inference engines

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

Unsloth

Unsloth AI · Training & fine-tuning

Open-source framework for fine-tuning and running LLMs with reduced memory, covering LoRA, QLoRA, full fine-tuning and RL, GGUF export, Dynamic quantizations and a local Studio/Desktop UI

Apache-2.0Open sourceFreeLocalSelf-hostedNov 2, 2026

vectorbt

Oleg Polakow · Financial analysis & investing

Python library for vectorized backtesting and portfolio analysis built on pandas, NumPy and Numba, with a commercial PRO edition

Apache-2.0 WITH Commons-ClauseFreePaidLocalNov 2, 2026

Vega-Altair

Vega-Altair developers (Vega project) · Data visualization

Declarative Python visualization library that compiles concise chart specifications to Vega-Lite JSON for interactive, grammar-of-graphics plots

BSD-3-ClauseOpen sourceFreeLocalNov 2, 2026

vLLM

vLLM project (originated at UC Berkeley Sky Computing Lab) · Local LLM inference & serving

In-depth entry

High-throughput LLM inference and serving engine with PagedAttention, continuous batching, quantization and an OpenAI-compatible server for GPU and accelerator clusters

Apache-2.0Open sourceFreeSelf-hostedNov 2, 2026

Whisper

OpenAI · Voice, vision & multimodal AI

OpenAI's open-source multilingual speech recognition model family with MIT-licensed code and weights, a Python package and CLI for transcription, translation and language identification

MITOpen sourceFreeLocalMaintenanceNov 2, 2026

yfinance

Ran Aroussi and contributors · Market & fundamentals data

Open-source Python library that downloads price history, fundamentals, options chains and fund data from Yahoo Finance's unofficial endpoints for research and education

Apache-2.0FreeOpen sourceLocalNov 2, 2026

Zipline Reloaded

Stefan Jansen (ML4Trading) · Financial analysis & investing

Community-maintained fork of Quantopian's Zipline, an event-driven Python backtester with data bundles and the Pipeline API

Apache-2.0Open sourceFreeLocalBroken

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