Directory

Microsoft's multi-agent framework (Core, AgentChat, Extensions, Studio) for Python and .NET, now archived with users directed to Microsoft Agent Framework

YAML-configured open-source framework for fine-tuning and post-training LLMs: full, LoRA and QLoRA training, preference and RL methods, multimodal models and multi-GPU or multi-node runs

Python framework for programming language-model pipelines with typed signatures and modules, then optimizing prompts and weights automatically against a metric

Open-source software that pools several Apple Silicon Macs (and Linux hosts) into one local inference cluster, sharding large models across devices with MLX

Python library for extracting validated structured data from LLM responses using Pydantic models, with automatic retries, streaming partials and support for many providers

Python library for NumPy-style array computing with composable transformations (jit, grad, vmap, shard_map) compiled through XLA to CPU, GPU and TPU

Open-source Python and JavaScript framework whose create_agent harness builds tool-using agents on the LangGraph runtime with swappable model providers and middleware

Low-level orchestration framework and runtime for stateful, long-running agents expressed as graphs, with durable execution, checkpointing, human-in-the-loop and streaming

C/C++ inference engine for LLMs and vision-language models with GGUF quantized weights, Metal, CUDA, Vulkan and other backends, a CLI and an OpenAI-compatible server

Open-source Python framework for retrieval-augmented agents over your data, with connectors, indexes, query engines and event-driven workflows, alongside the commercial LlamaParse document platform

Open-source vector database from Zilliz with Lite, Standalone and Distributed deployments, many index types and GPU acceleration

Apple's open-source array framework for machine learning on Apple Silicon, with NumPy-like Python, C++ and Swift APIs and unified CPU/GPU memory

Python package and CLI for running, serving, quantizing and fine-tuning large language models on Apple Silicon with MLX

Port of OpenAI's Whisper speech-recognition models to MLX, offering a CLI and Python API for local transcription on Apple Silicon

Open JSON-RPC standard for connecting AI applications to tools, data and prompts through servers, now stewarded under the Linux Foundation with SDKs in many languages

Open-source runtime and model manager for running open-weight LLMs locally on macOS, Windows and Linux, with a REST API, OpenAI- and Anthropic-compatible endpoints and optional cloud models

Lightweight open-source Python and TypeScript framework for agents, handoffs, guardrails, sessions and tracing, defaulting to OpenAI's Responses API with adapters for other providers

PostgreSQL extension adding vector types, distance operators and HNSW/IVFFlat indexes for similarity search inside the database

Type-safe Python agent framework from the Pydantic team with validated structured outputs, dependency injection, swappable model providers, MCP, durable execution and evals

Open-source deep-learning framework with eager tensors, autograd, torch.compile and distributed training, governed by the PyTorch Foundation and the base of most LLM tooling

Open-source Python library for evaluating LLM and RAG applications with LLM-driven and custom metrics, experiments, dataset management and result tracking

Open-source Python framework for distributing tasks, actors and ML workloads across a cluster, with libraries for data processing, training, tuning, serving and reinforcement learning

BSD-licensed Python machine-learning library for classification, regression, clustering, dimensionality reduction, preprocessing and model selection on NumPy and SciPy

Python library for computing and training embedding, cross-encoder reranker, sparse and multi-vector retrieval models, maintained by Hugging Face with thousands of pretrained models on the Hub